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bejel (endemic syphilis)

Epidemiology: - endemic non-venereal spirochete infection with Treponema pallidum subspecies endemicum - transmission is by close skin contact-sexual or not- primarily between children living in conditions of poor hygiene - occurs mainly in arid countries of the eastern Mediterranean & West Africa - transmission results from mouth-to-mouth contact or sharing eating & drinking utensils. Clinical manifestations: - typical primary, secondary & tertiary disease - initial mucocutaneous lesion followed by diffuse secondary lesions, a latent period, & late destructive disease - primary: mucous patch (usually on the buccal mucosa), which may go unnoticed - secondary: papulosquamous & erosive papular lesions of the trunk a & extremities similar to lesions of yaws - tertiary: - periostitis of the leg bones is common - later, gummatous lesions of the nose & soft palate Laboratory: - see syphilis - morphologically & serologically indistinguishable from the agent of syphilis Treponema pallidum subspecies pallidum Management: - penicillin

Specific

tertiary bejel

General

syphilis

References

  1. Cunha BA Bejel, Pinta, and Yaws Merck Manual http://www.merckmanuals.com/professional/sec14/ch174/ch174b.html