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breast carcinoma amplified sequence 1 (novel amplified in breast cancer 1, amplified & overexpressed in breast cancer, BCAS1, AIBC1, NABC1,)
Function:
1) interacts with DYNLL1 & DYNLL2 (putative)
2) phosphorylated on Ser-340
Structure:
- homodimer
Compartment: cytoplasm
Alternative splicing: named isoforms=2
Expression:
- expressed in brain, prostate > testis, intestine, colon
Pathology:
1) overexpressed in most breast cancer cell lines
2) down-regulated in some colorectal tumors
General
phosphoprotein
Properties
SIZE: MW = 62 kD
entity length = 584 aa
COMPARTMENT: cytoplasm
MOTIF: phosphorylation site
Database Correlations
OMIM 602968
UniProt O75363
References
UniProt :accession O75363