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basophilic stippling

Basophilic stippling represent multiple, punctate basophilic cytoplasmic inclusions. Clinical significance: seen in association with: 1) lead poisoning - sideroblastic anemia [2] 2) arsenic poisoning 3) thalassemia 4) myelofibrosis 5) alcohol abuse [2] Differential diagnosis: - Pappenheimer bodies (iron body)

Related

Pappenheimer body (iron body)

General

abnormal morphologic structure (malformation) cytology

References

  1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 414
  2. Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025