Search
basilar artery thrombosis/occlusion
Pathology:
1) brainstem dysfunction
2) mortality 60-70%
Clinical manifestations:
1) visual loss
2) diplopia
3) vertigo
4) ataxia
5) paresis
6) paresthesias
Management:
- intra-arterial vs intravenous thrombolysis with alteplase
- endovascular thrombectomy: 40% of patients with modified Rankin Scale score of 0-3 at 90 days vs 23% of controls [3]
- angioplasty or stenting after failed endovascular thrombectomy [3]
Related
basilar artery
General
basilar artery disease
arterial thrombosis
References
- Geriatrics Review Syllabus, American Geriatrics Society,
5th edition, 2002-2004
- Journal Watch 24(23):176, 2004
Lindsberg PJ, Soinne L, Tatlisumak T, Roine RO, Kallela M,
Happola O, Kaste M.
Long-term outcome after intravenous thrombolysis of basilar
artery occlusion.
JAMA. 2004 Oct 20;292(15):1862-6.
PMID: 15494584
- Jovin TG et al.
Trial of thrombectomy 6 to 24 hours after stroke due to basilar-artery occlusion.
N Engl J Med 2022 Oct 13; 387:1373.
PMID: 36239645
https://www.nejm.org/doi/10.1056/NEJMoa2207576
- Tao C et al.
Trial of endovascular treatment of acute basilar-artery occlusion.
N Engl J Med 2022 Oct 13; 387:1361.
PMID: 36239644
https://www.nejm.org/doi/10.1056/NEJMoa2206317