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bacterial lipopolysaccharide (LPS)
Function:
- endotoxin
Structure:
- main components of the external leaflet of the Gram-negative outer membrane
- 3 Components:
- lipid A (endotoxin component)
- core oligosaccharide
- O-polysaccharide
- detailed structure of lipopolysaccharide differs from one bacterium to another [2]
Interactions
molecular events
General
bacterial antigen
bacterial polysaccharide
endotoxin
lipopolysaccharide
mitogen
Properties
References
- Garcia-Vello P, Di Lorenzo F, Zucchetta D et al
Lipopolysaccharide lipid A: A promising molecule for new immunity-based therapies
and antibiotics.
Pharmacol Ther. 2022 Feb;230:107970.
PMID: 34454000 Review.
- Wang X, Quinn PJ.
Lipopolysaccharide: Biosynthetic pathway and structure modification.
Prog Lipid Res. 2010 Apr;49(2):97-107.
PMID: 19815028 Review.
Component-of
molecular complex