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bacteremia
The presence of viable bacteria in the circulating blood. (see sepsis)
Epidemiology:
- PCV13 vaccines have reduced incidence of bacteremia in young children & shifted the most-commonly isolated pathogens from pneumococcus to E coli, S aureus, & Salmonella [4]
Diagnostic criteria:
- absence of fever, elevated serum C-reactive protein & criteria for systemic inflammatory response syndrome with negative predictive value of 0.99 [3]
- a normal blood WBC count does not rule out bacteremia [2]
- shaking chills is a positive predictor of bacteremia
- normal food consumption is a negative predictor [5]
Interactions
disease interactions
Specific
gonococcemia
meningiococcemia (purpura fulminans)
sepsis
spirochetemia
streptococcemia
General
sign/symptom
References
- Stedman's Medical Dictionary 26th ed, Williams &
Wilkins, Baltimore, 1995
- Seigel TA et al.
Inadequacy of temperature and white blood cell count in
predicting bacteremia in patients with suspected infection.
J Emerg Med 2012 Mar; 42:254.
PMID: 20674238
- Anderson RE and Walls RM
Is My Patient Bacteremic?
NEJM Journal Watch. Aug 6, 2014
Massachusetts Medical Society
(subscription needed) http://www.jwatch.org
- Lindvig KP et al.
How do bacteraemic patients present to the emergency department
and what is the diagnostic validity of the clinical parameters;
temperature, C-reactive protein and systemic inflammatory
response syndrome?
Scand J Trauma Resusc Emerg Med. 2014 Jul 15;
PMID: 25027551
- Greenhow TL, Hung YY, Herz A.
Bacteremia in children 3 to 36 months old after introduction
of conjugated pneumococcal vaccines.
Pediatrics 2017 Apr; 139:e20162098.
PMID: 28283611
http://pediatrics.aappublications.org/content/early/2017/03/08/peds.2016-2098
- Komatsu T, Takahashi E, Mishima K et al.
A simple algorithm for predicting bacteremia using food
consumption and shaking chills: A prospective observational
study.
J Hosp Med 2017 Jul; 12:510.
PMID: 28699938