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Bacillus subtilis
found in soil and the gastrointestinal tract of ruminants and humans
Indications:
- probiotic
- 30 days of Bacillus subtilis eliminates 97% of Staphylococcus aureus in the gut
- affects colonizsation of Staphylococcus aureus in the nose
Dosage:
- 240 mg once a day
Capsules: 60 mg
Laboratory:
- Gram-positive, catalase-positive bacterium
- facultative aerobe
- Bacillus subtilis IgE in serum
Mechanism of action:
- does not kill Staphylococcus aureus, but diminishes its ability to colonize
General
Bacillus
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Wikipedia: Bacillus subtilis
https://en.wikipedia.org/wiki/Bacillus_subtilis
- Kunst F, Ogasawara N, Moszer I et al
The complete genome sequence of the gram-positive bacterium
Bacillus subtilis.
Nature. 1997 Nov 20;390(6657):249-56.
PMID: 9384377
http://www.nature.com/nature/journal/v390/n6657/full/390249a0.html
- Hein I
Probiotic Proves Its Might for Staph Decolonization.
Bacillus subtilis eliminated most S. aureus in the gut, and without harming
microbiome.
MedPage Today January 19, 2023
https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/102709
- Piewngam P, Khongthong S, Roekngam N
Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand:
a phase 2, double-blind, randomised, placebo-controlled trial.
Lancet Microbe. 2023 Jan 13:S2666-5247(22)00322-6.
PMID: 36646104
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00322-6/fulltext