B cell markers

Include: - CD10 (pre-B cells, germinal center cells, neutrophils, pre-B ALL, Burkitt lymphoma and follicular lymphoma) - CD19 (appears early in B cell differentiation and persists through maturation until plasma cell stage; need frozen tissue), - CD20 (appears later in B cell maturation and persists until plasma cell stage), - CD21, CD22 (expressed at later stages of maturation) - CD23 (follicular dendritic reticulum cells, sIgM/sIgD double positive B cells and small lymphocytic lymphoma - CD25 (small lymphocytic lymphoma, mantle cell lymphoma) - CD34 & TdT (very immature cells) - CD43 (activated B cells, T cells, neutrophils) low grade B cell lymphomas except follicular lymphoma) - CD79a (B precursor cells before CD19, stops before plasma cell stage) - HLA-DR, Fc receptors, complement receptors

References

Ioachim & Ratech. Ioachim's Lymph Node Pathology. 3rd ed. Lippincott, Williams & Wilkins, 2002