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hormonally up-regulated neu tumor-associated kinase; B19; serine/threonine protein kinase MAK-V (HUNK, MAKV)
Function:
- Ser/Thr protein kinase
Structure:
- belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily contains 1 protein kinase domain
Related
receptor tyrosine-protein kinase erbB-2; p185erbB2; C-erbB-2; NEU proto-oncogene; tyrosine kinase-type cell surface receptor HER2; MLN 19; CD340 (ERBB2, HER2, NEU, NGL)
General
serine/threonine kinase
Properties
SIZE: entity length = 714 aa
MW = 80 kD
STATE: active state
MOTIF: kinase domain
SITE: 62-320
MOTIF: ATP-binding site
NAME: ATP-binding site
SITE: 68-76
ATP-binding site
NAME: ATP-binding site
SITE: 91-91
aspartate residue {D186}
S/T phosphorylation site
Database Correlations
OMIM 606532
UniProt P57058
Pfam PF00069
Entrez Gene 30811
Kegg hsa:30811
ENZYME 2.7.11.1
References
UniProt :accession P57058