Contents

Search


5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase- associated protein 1, Nak-associated protein 1, TILP, AZI2, NAP1)

Function: - activates serine/threonine protein kinase TBK1 & facilitates its oligomerization - enhances phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 - promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B - participates in IFN-beta promoter activation via TICAM1 - interacts with IKBKE, TBK1 & TICAM1 Compartment: cytoplasm Alternative splicing: named isoforms=3 Expression: - widely expressed - abundant expression seen in pancreas & testis

General

other protein

Properties

SIZE: MW = 45 kD entity length = 392 aa COMPARTMENT: cytoplasm MOTIF: coiled coil {40-76} coiled coil {102-196} TBK1 interaction {158-270}

Database Correlations

UniProt Q9H6S1

References

UniProt :accession Q9H6S1