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vacuolar ATP synthase 16 kD proteolipid subunit; V-type proton ATPase 16 kD proteolipid subunit; V-ATPase 16 kD proteolipid subunit; vacuolar proton pump 16 kD proteolipid subunit (ATP6V0C, ATP6C, ATP6L, ATPL)
Function:
- proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase
- interacts with LASS2.
- interacts with HTLV-1 accessory protein p12I
Structure: belongs to the V-ATPase proteolipid subunit family
Compartment: vacuole membrane
General
protein subunit
transmembrane 4e protein
Properties
SIZE: MW = 16 kD
entity length = 155 aa
MOTIF: exoplasmic domain {1-10}
transmembrane domain {11-33}
cytoplasmic loop {34-55}
transmembrane domain {56-76}
exoplasmic loop {77-92}
transmembrane domain {93-114}
cytoplasmic loop {115-126}
transmembrane domain {127-152}
exoplasmic domain {153-155}
Database Correlations
OMIM 108745
UniProt P27449
Pfam PF00137
Entrez Gene 527
Kegg hsa:527
References
UniProt :accession P27449
Component-of
vacuolar ATP synthase (v ATPase) or endomembrane proton pump