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astrocyte
Function:
- neuroglial cells involved in supportive functions
- interactions with neurons & capillaries forming blood brain barrier
- astrocytes involved in re-uptake of glutamate at excitatory synapses (allegedly over 95%
Comparative biology:
- astrocytic synthesis of the chemokines CXCL1 & CCL2 in response to cytokine challenges with IL-1-beta or TNF-alpha are exaggerated in mice with ME7 prion disease [1]
Related
astrocytoma (astrocytic neoplasm)
Specific
Alzheimer type I astrocyte
Alzheimer type II astrocyte
fibrillary astrocyte
gemistocytic astrocyte
protoplasmic astrocyte
General
neuroglia
Properties
WITHIN: central nervous system
References
- Hennessy E, Griffin EW, Cunningham C
Astrocytes Are Primed by Chronic Neurodegeneration to Produce
Exaggerated Chemokine and Cell Infiltration Responses to Acute
Stimulation with the Cytokines IL-1beta and TNF-alpha.
The Journal of Neuroscience, 3 June 2015, 35(22): 8411-8422
http://www.jneurosci.org/content/35/22/8411