Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein, ASH2L)

Function: - component of the Set1/Ash2 histone methyltransferase complex - transcriptional regulator (putative) - role in hematopoiesis (putative) - interacts with HCFC1 Structure: - contains 1 B30.2/SPRY domain Compartment: nucleus Alternative splicing: named isoforms=3 Expression: - ubiquitously expressed - predominantly expressed in adult heart & testis & fetal lung and liver - barely detectable expression in adult lung, liver, kidney, prostate, & peripheral leukocytes

General

protein subunit zinc finger protein

Properties

SIZE: MW = 69 kD entity length = 628 aa COMPARTMENT: cell nucleus MOTIF: Zn finger C4-type SITE: 117-150 EFFECTOR-BOUND: Zn+2 B30.2/SPRY {360-583}

Database Correlations

OMIM 604782 UniProt Q9UBL3 Pfam PF00622

References

UniProt :accession Q9UBL3