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AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2, BRG1-associated factor 200, BAF200, ARID2, KIAA1557)
Function:
- role in transcriptional activation & repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology)
- stabilizes SWI/SNFB chromatin remodeling complex
- role in targeting SWI/SNFB complex to different genes
Structure: contains 1 ARID domain
Compartment: nucleus
Alternative splicing: named isoforms=3
General
AT-rich interactive domain-containing protein (ARID domain-containing protein, ARID)
Properties
SIZE: MW = 197 kD
entity length = 1835 aa
COMPARTMENT: cell nucleus
MOTIF: ARID {13-105}
LXXL {313-317}
glutamine-rich region {793-1128}
MOTIF: glutamine residue (SEVERAL)
Database Correlations
UniProt Q68CP9
Pfam PF01388
References
UniProt :accession Q68CP9
Component-of
SWI/SNF-B (PBAF) chromatin remodeling complex