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Arf GTPase-activating (Arf-GAP) domain

Involved in hydrolysis of GTP bound to ARF. Consists of a 3-stranded beta-sheet surrounded by 5 alpha helices. The domain is organized around a central Zn+2 coordinated by 4 cysteines. The zinc finger motif has some similarity to the C4-type GATA zinc finger.

General

GTPase-activating (GAP) domain

Properties

NAME: Arf-GAP domain

References

prosite :accession PS50115