Contents

Search

apolipoprotein B in serum/plasma

see apolipoprotein A1/B in serum Indications: - evaluation of dyslipidemia - improves risk prediction for cardiovascular events when added to other traditional risk factors for men > 35 years, women > 45 years (NGC) - better indicator of cardiovascular risk than LDL cholesterol in statin- treated patients [1] - only lipid parameter independently associated with risk for myocardial infarction [2] Clinical significance: - serum apoB > 130 mg/dL is a risk modifier in patients not using statins - in statin-treated patients, serum apoB target of < 92 mg/dL may be appropriate [1]

Related

apolipoprotein A1/B in serum apolipoprotein B

Specific

apolipoprotein B100 in serum

General

apolipoprotein in serum/plasma

References

  1. Wendling P ApoB May Better Predict Mortality Risk in Statin-Treated Patients. Medscape - Mar 17, 2021. https://www.medscape.com/viewarticle/947631 - Lindhardt Johannesen CD, Mortensen MB, Langsted A, Nordestgaard BG, Apolipoprotein B and Non-HDL Cholesterol Better Reflect Residual Risk Than LDL Cholesterol in Statin-Treated Patients. J Am Coll Cardiol 2021. 77(11):1439-1450 PMID: 33736827 https://www.jacc.org/doi/10.1016/j.jacc.2021.01.027 - Stone NJ, Lloyd-Jones D Tracking Residual Risk: Time for a Change? J Am Coll Cardiol 2021. 77(11):1451-1453 PMID: 33736828 https://www.jacc.org/doi/10.1016/j.jacc.2021.01.035
  2. Marston NA, Giugliano RP, Melloni GEM et al. Association of apolipoprotein B-containing lipoproteins and risk of myocardial infarction in individuals with and without atherosclerosis: Distinguishing between particle concentration, type, and content. JAMA Cardiol 2021 Nov 13; [e-pub]. PMID: 34773460 PMCID: PMC8590731 (available on 2022-11-13) https://jamanetwork.com/journals/jamacardiology/article-abstract/2786333 - Sniderman AD, Navar AM, Thanassoulis G et al. Apolipoprotein B vs low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol as the primary measure of apolipoprotein B lipoprotein- related risk: The debate is over. JAMA Cardiol 2021 Nov 13; [e-pub]. PMID: 34773457 https://jamanetwork.com/journals/jamacardiology/article-abstract/2786334

Component-of

apolipoprotein B/apolipoprotein A1 in serum/plasma apolipoprotein B/LDL cholesterol in serum/plasma cholesterol LDL/apolipoprotein B in serum/plasma cholesterol/apolipoprotein B in serum/plasma