AP-2 complex subunit beta-1; adapter-related protein complex 2 beta-1 subunit; beta2-adaptin; beta-adaptin; plasma membrane adaptor HA2/AP2 adaptin beta subunit; clathrin assembly protein complex 2 beta large chain; AP105B (AP2B1, ADTB2, CLAPB1)

Function: - component of clathrin-associated adaptor protein complex 2 (AP-2) - binds EPN1, EPS15, SNAP91 & clathrin Structure: - belongs to the adaptor complexes large subunit family Compartment: - cell membrane, coated pit - peripheral membrane, cytoplasmic side - component ofthe coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane Alternative splicing: named isoforms=2

General

beta adaptin (adaptor-related protein complex, beta subunit) phosphoprotein

Properties

SIZE: entity length = 937 aa MW = 105 kD COMPARTMENT: cytoplasm MOTIF: proline-rich region SITE: 576-716 MOTIF: proline residue (SEVERAL) Tyr phosphorylation site {Y737} Tyr phosphorylation site {Y888}

Database Correlations

OMIM 601025 UniProt P63010 PFAM correlations Entrez Gene 163 Kegg hsa:163

References

UniProt :accession P63010