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topical antiseptic

Product with antimicrobial activity designed for use on skin or other superficial tissues; may damage cells. Home antiseptics of no benefit in preventing infectious disease. [1] Antibacterial soap no better than ordinary soap. [4,5] Single-use packaging for OTC products [3] over-the-counter hand soaps & body washes can no longer contain certain topical antibacterial agents triclosan & triclocarban [5]

Related

disinfectant

Specific

acriflavine benzethonium (Salanine, BZT, Diapp, Quatrachlor, Polymine D, Phemithyn, Antiseptol, Disilyn, Phermerol) boric acid brilliant green (Malachite green G, Emerald green, Solid green JJO, Diamond green G, Aniline green, Benzaldehyde green, Fast green J) cetrimide; alkyltrimethylammonium bromide cetylpyridinium (Cepacol) chlorhexidine (Peridex, Hibiclens, Nolvasan, Bactigras, Arlacide H) chlorine dioxide chloroxylenol; 4-chloro-3,5-dimethylphenol dequalinium chloride ethanol topical (Avant, Triseptin) hand antiseptic; hand sanitzer (alcohol-based hand rub) hexachlorophene (pHisoHex, Isobac) hexylresorcinol (Bradosol) hypochlorous acid (HClO) merbromin (Mercurochrome, Merbromine, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept, Cinfacromin) mouthwash NewSkin oxychlorosene phosphoric acid (H3PO4) povidone-iodine (Betadine) proflavine; diaminoacridine Purell Sal acid (salicylic acid 40% plaster) silver nitrate (AgNO3) sodium chlorite (NaClO2) thymol; 6-isopropyl-m-cresol; 5-methyl-2-isopropylphenol; 5-methyl-2-propan-2-ylphenol trichloroacetate triclosan (Irgasan, Cloxifenolum, Triclosanum, Cliniclean, Cloxifenol, Tersaseptic, Aquasept, Manusept, Sapoderm)

General

topical agent

References

  1. Journal Watch 24(7):53, 2004 Larson EL, Lin SX, Gomez-Pichardo C, Della-Latta P. Effect of antibacterial home cleaning and handwashing products on infectious disease symptoms: a randomized, double-blind trial. Ann Intern Med 140:321, 2004 PMID: 14996673
  2. Prescriber's Letter 12(12): 2005 Efficacy and Safety of Antibacterial Soaps for Home Use Detail-Document#: 211205 (subscription needed) http://www.prescribersletter.com
  3. FDA MedWatch. Nov 13, 2013 Over-the-Counter Topical Antiseptic Products: Drug Safety Communication - FDA Requests Label Changes and Single-Use Packaging to Decrease Risk of Infection. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm374892.htm
  4. FDA News Release: Dec. 16, 2013 FDA issues proposed rule to determine safety and effectiveness of antibacterial soaps. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm378542.htm
  5. Prescriber's Letter 21(2): 2014 FDA to Evaluate the Safety and Effectiveness of Antibacterial Soaps. Detail-Document#: 300208 (subscription needed) http://www.prescribersletter.com
  6. FDA News Release. Sept 2, 2016 FDA issues final rule on safety and effectiveness of antibacterial soaps. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm517478.htm