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antinuclear antibody (ANA)

see anti-nuclear antibody in serum Etiology: - systemic lupus erythematosus (SLE)* - scleroderma - Sjogren's syndrome - mixed connective tissue disease * 95% sensitivity, poor specificity [1]

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anti-nuclear antibody (ANA) in serum

General

autoantibody

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, 18. American College of Physicians, Philadelphia 2015,2018.
  2. ARUP Consult: Antinuclear Antibody Disease Testing Algorithm https://arupconsult.com/algorithm/antinuclear-antibody-testing-algorithm - Antinuclear Antibody (ANA) with HEp-2 Substrate https://arupconsult.com/ati/antinuclear-antibody-ana-hep-2-substrate