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anti-Tr antibody
Etiology:
1) cerebellar degeneration
2) associated malignancy
-> Hodgkin's lymphoma
Pathology:
Neuronal antigen:
-> neuronal cytoplasm, Purkinje cells, spiny dendrites
Laboratory:
- TR antibody in body fluid
General
paraneoplastic autoantibody
References
Stuve O & Zamvil SS. In: Medical Immunology 10th edition
(2001), Section 3, Clinical Immunology. 38. Neurologic diseases.