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anti-thyroid peroxidase (microsomal) antibody

Thyroid peroxidase is the main & possibly only autoantigenic component of microsomes. Etiology: 1) Hashimoto's thyroiditis (90%) - titers of 1:2500 are diagnostic of Hashimoto's thyroiditis 2) idiopathic myxedema 3) Graves' disease 4) postpartum form of subacute lymphocytic thyroiditis (some)

Related

Hashimoto's thyroiditis; chronic lymphocytic thyroiditis; struma lymphomatosa; lymphadenoid goiter; primary myxedema thyroid peroxidase thyroid peroxidase (microsomal) antibody in serum

General

autoantibody

References

  1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 648
  2. Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
  3. Medical Knowledge Self Assessment Program (MKSAP) 15, 16. 17 American College of Physicians, Philadelphia 2009, 2012, 2015