anti-parietal cell antibody (PCellAb)

also see parietal cell antibody in serum Etiology: 1) common in: a) 95% of patients with pernicious anemia - 60% of patients with pernicious anemia also have intrinsic factor-blocking antibodies b) up to 50% of patients atrophic gastritis without pernicious anemia 3) 25-30% of patients with autoimmune thyroiditis 2) lower frequency associated with: - Addison's disease - myasthenia gravis - juvenile diabetes mellitus - gastric ulcer - iron-deficiency anemia - Sjogren's syndrome

Related

parietal cell parietal cell antibody (PCellAb) in serum pernicious anemia; autoimmune gastritis

References

Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995