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annexin A8; annexin-8; annexin VIII; vascular anticoagulant-beta; VAC-beta (ANXA8, ANX8)

Function: - anticoagulant protein - acts as an indirect inhibitor of thromboplastin Structure: - pair of annexin repeats may form one binding site for Ca+2 & phospholipid - belongs to the annexin family - contains 4 annexin repeats

General

annexin endogenous anticoagulant

Properties

SIZE: entity length = 327 aa MW = 37 kD MOTIF: Annexin {30-90} Annexin {102-162} Ca+2-binding site binding site FOR-BINDING-OF: phospholipid Annexin {187-247} Annexin {262-322}

Database Correlations

OMIM 602396 UniProt P13928 Pfam PF00191 LOCUS-LINK correlations KEGG correlations

References

  1. UniProt :accession P13928
  2. Entrez Gene :accession 244