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androstenedione in serum

Indications: 1) useful in conjunction with other tests in evaluation & management of androgen disorders a) androgen excess b) androgen deficiency 2) monitoring of glucocorticoid treatment of congenital adrenal hyperplasia Specimen: 1) serum 2) place on ice & process in 1 hour 3) store frozen 4) specimen should be collected at least 1 week before or after menstrual period Reference values: 1) male (adult): 75-205 ng/dL (2.6-7.2 nmol/L) 2) female (adult): 85-275 ng/dL (3.0-9.6 nmol/L) 3) prepurtal: 8-50 ng/dL (0.3-1.7 nmol/L) Increases: 1) clinical disorders a) polycystic ovary disease (some) b) hirsuitism (some) c) congenital adrenal hyperplasia d) Cushing's syndrome e) ectopic ACTH-producing tumor f) hyperplasia of ovarian stroma g) ovarian tumor h) osteoporosis in females 2) pharmaceutical agents -> in vivo effects -> corticotropin, clomiphene, cyproterone acetate, levonorgestrel, metyrapone Decreases: 1) clinical disorders a) sickle cell anemia b) adrenal failure c) ovarian failure 2) pharmaceutical agents -> in vivo effects -> dexamethasone

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androstenedione

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androstenedione in body fluid

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Androstenedione by TMS Laboratory Test Directory ARUP: 2001638
  3. Panel of 5 tests Laboratory Test Directory ARUP: 2001763
  4. Panel of 3 tests Laboratory Test Directory ARUP: 2002028
  5. Panel of 3 tests Laboratory Test Directory ARUP: 2002029
  6. Panel of 4 tests Laboratory Test Directory ARUP: 2002281
  7. Panel of 5 tests Laboratory Test Directory ARUP: 2002282
  8. Panel of 4 tests Laboratory Test Directory ARUP: 2002283