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androstenedione

A major precursor in the biosynthesis of androgens & estrogens. It is produced in the adrenals & gonads & serves as a prohormone for testosterone & estrone, especially in postmenopausal women. Pharmacology: Used as a popular ergogenic agent. However, at doses of 100 mg BID, does NOT increase serum testosterone or maximum strength in weight-training men & results in significantly increased LDL/HDL ratio after 12 weeks of use [2]. Monitor: liver function tests

Interactions

molecular events drug adverse effects of androgens

Related

androstenedione in serum steroid biosynthesis

General

17 ketosteroid adrenal cortex hormone; corticosteroid androgen or anabolic steroid androstene

Database Correlations

PUBCHEM correlations

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Journal Watch 21(1):1, 2001 Broeder et al Arch Intern Med 160:3093, 2001
  3. Prescriber's Letter 8(8):48 2001