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amyloid typing

Indications: - evaluation of amyloidosis Procedure: - protein sequencing of amyloid obtained on biopsy - immunofluoresence or immunohistochemistry of biopsy material - laser microdissection & mass-spectroscopy-based proteomic analysis [2] Note: there is no corresponding Loinc for this test

General

special chemistry test

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
  2. Vrana JA, Gamez JD, Madden BJ et al Classification of amyloidosis by laser microdissection and mass spectrometry-based proteomic analysis in clinical biopsy specimens. Blood. 2009 Dec 3;114(24):4957-9. PMID: 19797517