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ampulla of Vater adenoma
Etiology:
- risk factors
a) familial adenomatous polyposis
b) Lynch syndrome (HNPCC)
Pathology:
- tumors may arise from bile duct, pancreatic duct or duodenum
Clinical manifestations:
- painless jaundice
- gastric outlet obstruction (duodenal obstruction)
Laboratory:
- no specific markers
Special laboratory:
- ERCP & endoscopic ultrasound
a) tissue sampling
b) decompression of obstruction via placing a stent
- upper gastrointestinal endoscopy & colonoscopy for surveillance of hereditary polyposis syndrome (familial adenomatous polyposis, Lynch syndrome)
Differential diagnosis: -ampulla of Vater adenocarcinoma
Management:
- presumably surgical excision (polypectomy) if no evidence of advanced disease
Related
ampulla of Vater (hepatopancreatic, bilaropancreatic ampulla)
ampulla of Vater adenocarcinoma
General
adenoma
References
- NEJM Knowledge+