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amnesia
Disturbance of long-term memory characterized by an inability to recall past experiences & a disturbance in learning new information. It is generally anterograde or ongoing, but also may include include retrograde amnesia for events that occurred just prior to a cerebral insult.
Etiology:
1) dementia
2) head trauma
3) stroke
4) Korsakoff's psychosis
5) seizure (temporal lobe)
6) anoxic injury to the hippocampus
a) hippocampal sclerosis
b) limbic encephalitis
c) Herpes encephalitis
7) psychogenic amnesia
8) drugs: fentanyl + cocaine (case report) [3]
Pathology:
-> injury to the limbic system
a) hippocampi (bilateral)
b) midline limbic structures
Clinical manifestations:
- memory impairment
Related
dementia; Alzheimer's disease & related dementias (ADRD)
head injury
Korsakoff's syndrome (amnesic psychosis)
limbic system
memory
seizure; epileptic seizure
stroke; cerebrovascular accident (CVA)
Specific
transient global amnesia
General
sign/symptom
References
- Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999
- Mendez M. Comprehensive Geriatric Assessment, Osterweil et al
eds, McGraw Hill, New York, 2000, pg 77
- Duru UB, Pawar G, Barash JA et al
An Unusual Amnestic Syndrome Associated With Combined Fentanyl
and Cocaine Use.
Ann Intern Med. 2018. Jan 30
PMID: 29379942
http://annals.org/aim/article-abstract/2671032/unusual-amnestic-syndrome-associated-combined-fentanyl-cocaine-use