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amlodipine/indapamide/telmisartan
Indications:
- initial treatment of hypertension
Dosage:
- telmisartan: 10 mg, indapamide: 0.625 mg, amlodipine: 1.25 mg
- telmisartan: 20 mg, indapamide: 1.25 mg, amlodipine: 2.5 mg
Mechanism of action:
- angiotensin-2 receptor antagonist, calcium channel blocker, thiazide diuretic combination
General
antihypertensive combination
References
- Rodgers A, Salam A, Schutte AE, et al.
Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination Compared
With Placebo for Initial Treatment of Hypertension.
J Am Coll Cardiol. 2024 Aug 30:S0735-1097(24)08227-5.
PMID: 39217570
- Ojji DB, Salam A, Sani MU
Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in
Nigeria: A Randomized Clinical Trial.
JAMA. 2024 Oct 1;332(13):1070-1079.
PMID: 39215620 PMCID: PMC11366076 (available on 2025-03-03) Clinical Trial.
- Rodgers A, Salam A, Schutte AE et al
Efficacy and safety of a novel low-dose triple single-pill combination of
telmisartan, amlodipine and indapamide, compared with dual combinations for
treatment of hypertension: a randomised, double-blind, active-controlled,
international clinical trial.
Lancet. 2024 Oct 19;404(10462):1536-1546.
PMID: 39426836 Clinical Trial.
Components
amlodipine (Norvasc, Amlocard, Amvaz)
indapamide (Lozol)
telmisartan (Micardis)