AML-M0; acute myeloblastic leukemia minimally differentiated

Epidemiology: 1) ~2% of AML cases 2) usually older men Microscopic Pathology: - nongranular myeloblasts, may resemble lymphoblasts Immunophenotype: - CD13, CD33, TdT, CD2, CD4, CD7, CD71 positive - myeloperoxidase variable - CD14, CD36, CD64 mostly negative - CD41, CD61, glycophorin A & most lymphocyte antigens negative

References

http:\www.pathologyoutlines.com/leukemia.html Feb 7, 2002