aminopeptidase

A group of enzymes catalyzing removal of the N-terminal amino acid from a polypeptide. Found in intestinal secretions.

Specific

5-oxoprolinase (OPLAH, 5-oxo-L-prolinase, pyroglutamase, pyroglutamate aminopeptidase, pyrrolidonecarboxylate peptidase, OPLAH) alanyl aminopeptidase aminopeptidase B; AP-B; arginine aminopeptidase; arginyl aminopeptidase (RNPEP, APB) aminopeptidase NPEPL1 (NPEPL1, KIAA1974) aminopeptidase O; AP-O (AOPEP, C9orf3, ONPEP) aminopeptidase-P archaemetzincin-1 (archeobacterial metalloproteinase-like protein 1, AMZ1, KIAA1950) arginyl aminopeptidase-like 1; RNPEP-like 1 (RNPEPL1) aspartyl aminopeptidase (DNPEP) CD13; aminopeptidase-N; aminopeptidase-M; gp150; microsomal aminopeptidase; alanine aminopeptidase (ANPEP, PEPN) cytosol aminopeptidase; leucine aminopeptidase-3; LAP3; proline aminopeptidase; peptidase S (LAP3, LAPEP, PEPS) dipeptidyl peptidase 2; dipeptidyl aminopeptidase II; dipeptidyl peptidase 7; dipeptidyl peptidase II; DPP II; quiescent cell proline dipeptidase (DPP7, DPP2, QPP) dipeptidyl peptidase 3; dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; dipeptidyl peptidase III; DPP III (DPP3) endoplasmic reticulum aminopeptidase 1; ARTS-1; adipocyte-derived leucine aminopeptidase; A-LAP; aminopeptidase PILS; puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator (ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154) endoplasmic reticulum aminopeptidase 2 (leukocyte-derived arginine aminopeptidase, L-RAP, ERAP2, LRAP) glutamyl aminopeptidase; EAP; aminopeptidase A; AP-A; differentiation antigen gp160; CD249 (ENPEP) leucyl-cystinyl aminopeptidase (LNPEP, cystinyl aminopeptidase, oxytocinase, OTase, insulin-regulated membrane aminopeptidase, insulin-responsive aminopeptidase, IRAP, placental leucine aminopeptidase, P-LAP) methionine aminopeptidase 1; MAP 1; MetAP 1; peptidase M 1 (METAP1, KIAA0094) methionyl aminopeptidase puromycin-sensitive aminopeptidase; PSA; cytosol alanyl aminopeptidase; arylamidase AAP-S (NPEPPS, PSA) thyrotropin-releasing hormone-degrading ectoenzyme; TRH-DE; TRH-degrading ectoenzyme; EC=3.4.19.6; pyroglutamyl-peptidase II; PAP-II; TRH-specific aminopeptidase; thyroliberinase (TRHDE) tripeptidyl peptidase 2 (tripeptidyl aminopeptidase, TPP2) tripeptidyl-peptidase 1; TPP-1; cell growth-inhibiting gene 1 protein; lysosomal pepstatin-insensitive protease; LPIC; tripeptidyl aminopeptidase; tripeptidyl-peptidase I; TPP-I (TPP1, GIG1, UNQ267/PRO304) Xaa-Pro aminopeptidase (XPNPEP) zinc aminopeptidase

Properties

MOTIF: active site

References

Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999