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alveolar rhabdomyosarcoma (rhabdomyosarcoma-2)
Genetics:
- associated with chromosomal translocations
- t(2;13)(q35;q14) with fusion of PAX3 & FKHR genes
- t(1;13)(p36;;q14) with fusion of PAX7 & FKHR (FOXO1A) genes
Clinical manifestations: Infrequently metastasis to breast in female patients
Immunohistochemistry: see rhabdomyosarcoma CD99 + ~10% of cases
Interactions
disease interactions
Related
chromosomal translocation t(2;13)(q35;q14)
chromosomal translocation t1p36:13q14
General
rhabdomyosarcoma (Sarcoma Botryoides)
Database Correlations
OMIM 268220