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aluminum osteodystrophy
Etiology:
- chronic aluminum-containing antacids
Pathology:
- low bone turnover state
Laboratory:
1) serum calcium: hypercalcemia
2) serum PTH low
3) serum 1,25-dihydroxyvitamin D3 low
4) serum alkaline phosphatase levels are NOT increased
4) complete blood count: microcytic anemia is common
5) bone marrow biopby: iliac crest biopsy for diagnosis
Management: deferoxamine chelation
General
osteodystrophy
References
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 617
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998