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hypoaldosteronism; mineralocorticoid deficiency
Diminished secretion of aldosterone.
Etiology:
1) Addison's disease
2) pharmacologic agents
a) non-steroidal anti-inflammatory drugs (NSAIDs)
b) heparin
c) ACE inhibitors
3) genetic diseases
Laboratory:
1) plasma aldosterone low
2) plasma 18-hydroxycorticosterone* (low, normal or high)
3) serum sodium (hyponatremia)
4) serum potassium (hyperkalemia)
* immediate precursor of aldosterone
Related
hyperaldosteronism
pseudohypoaldosteronism
Specific
Addison's disease (primary adrenal failure)
developmental disorder of aldosterone deficiency
hyporeninemic hypoaldosteronism
General
sign/symptom
References
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015