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alarm features of dyspepsia
Clinical manifestations:
1) age > 55 years with new-onset symptoms
2) family history of proximal gastrointestinal cancer
3) unintentional weight loss
4) gastrointestinal bleeding
5) history of peptic ulcer
6) progressive dysphagia, odynophagia
7) unexplained iron-deficiency anemia
8) persistent vomiting
9) palpable mass or lymphadenopathy
10) gastric surgery
11) jaundice (not mentioned in [1])
12) diaphoresis, unexplained fatigue, nausea, vomiting, exertional symptoms suggest angina pectoris masquerading as dyspepsia
Special laboratory:
- upper gastrointestinal endoscopy
- electrocardiogram if any doubt this could be angina pectoris*
* atypical presentations of cardiac ischemia & myocardial infarction are more common in women, older adults, & patients with diabetes mellitus
Related
dyspepsia (indigestion)
General
red flag
References
- Medical Knowledge Self Assessment Program (MKSAP) 17, 18.
American College of Physicians, Philadelphia 2015, 2018.