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alanyl tRNA synthetase (alanine-tRNA ligase, AlaRS, NY-REN-42 antigen)
Function:
ATP + L-alanine + tRNA(Ala)
AMP + diphosphate + L-alanyl-tRNA(Ala)
Structure:
- monomer
- belongs to the class-II aminoacyl-tRNA synthetase family
Compartment: cytoplasm (putative)
General
amino acyl tRNA synthetase-2
phosphoprotein
Properties
SIZE: entity length = 968 aa
MW = 107 kD
COMPARTMENT: cytoplasm
MOTIF: active site
SITE: 1-497
MOTIF: acetylation site
SITE: 1-1
EFFECTOR-BOUND: acetyl
Thr phosphorylation site {T578}
Tyr phosphorylation site {Y580}
Database Correlations
OMIM 601065
UniProt P49588
PFAM correlations
Entrez Gene 16
Kegg hsa:16
ENZYME 6.1.1.7
References
UniProt :accession P49588