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adult-onset asthma

Pathology: - tends to be non-allergic - inflammation along the entire respiratory tract, with sinusitis, nasal polyps & sputum eosinophilia associated with severe cases - systemic inflammation associated with severe cases Clinical manifestations: - can be relatively mild and easy to control or can be severe & treatment resistant Laboratory: - complete blood count - neutrophilia associated with severe cases - sputum eosinophils increased in severe cases Management: - see asthma

General

asthma

References

  1. Amelink M et al. Severe adult-onset asthma: A distinct phenotype. J Allergy Clin Immunol 2013 Aug; 132:336 PMID: 23806634 http://www.jacionline.org/article/S0091-6749(13)00699-4/abstract