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Adrenocortical dysplasia protein homolog (POT1 & TIN2-interacting protein) (ACD PIP1 PTOP)
Function:
- role of telomeric regulator as component of TRF1 complex controlling telomere length
- controls POT1 telomeric recruitement & telomere elongation by inhibition of telomerase activity
- may play a role in organogenesis
- forms heterodimers with POT1
- interacts with TINF2
- component of TRF1 complex
Compartment: nucleus (putative)
Alternative splicing: named isoforms=2
Related
adrenal cortex
General
other protein
Properties
SIZE: MW = 58 kD
entity length = 544 aa
COMPARTMENT: cell nucleus
MOTIF: PWI {97-99}
POT1 interaction {244-337}
serine-rich region {354-442}
MOTIF: serine residue (SEVERAL)
Database Correlations
UniProt Q96AP0
References
UniProt :accession Q96AP0