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adrenochrome
Function:
- formed by oxidation of adrenaline
- may be produced normally as an intermediate in the formation of neuromelanin
- adrenochrome is metabolized at least partially by glutathione-S-transferase
Pharmacology:
- no current medical uses
Pathology:
- in the 1950s a hypothesis that adrenochrome may play a role in schizophrenia
- In 1973, the American Psychiatric Association reported methodological flaws in work associating adrenochrome with schizophrenia
- no reliable reports of adrenochome identified in patients with schizophrenia
Notes:
- the chrome suffix refers to its color.
- pure adrenochrome is deep violet
- adrenochrome is the subject of a QAnon conspiracy theory that alledges politicians & Hollywood elites engage in producing fear in children during Satanic rituals to harvest epinephrine from the frightened children's blood for use in producing adrenochrome* as an elixer to remain young [2]
* Toronto Research Chemicals sells adrenochrome 25 mg for $127, 100 mg for $391 stable for shipping at room temperature
Interactions
drug adverse effects (more general classes)
General
epinephrine; adrenaline (Sus-Phrine, Vapronefrin, Epifrin, Glaucon, Auvi-Q, Allerject)
Properties
AGONIST-FOR: beta adrenergic receptor
Database Correlations
PUBCHEM cid=5898
References
- Wikipedia: Adrenochrome
https://en.wikipedia.org/wiki/Adrenochrome
- Wikipedia: QAnon
https://en.wikipedia.org/wiki/QAnon
- Toronto Research Chemicals
A305250
https://www.trc-canada.com/product-detail/?A305250
- Costa VM, Silva R, Ferreira LM et al
Oxidation process of adrenaline in freshly isolated rat cardiomyocytes:
formation of adrenochrome, quinoproteins, and GSH adduct.
Chem Res Toxicol. 2007 Aug;20(8):1183-91.
PMID: 17630707 Free article.