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adaptin
Function:
- adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles
- clathrin-associated protein complexes interact with the cytoplasmic tails of membrane proteins, leading to their selection & concentration (putative)
Related
clathrin (triskelion)
HA/AP adaptor complex
Specific
alpha adaptin (adaptor-related protein complex 2, alpha subunit, clathrin adaptor complex AP2, alpha subunit)
AP-4 complex subunit epsilon-1; adapter-related protein complex 4 subunit epsilon-1; AP-4 adapter complex subunit epsilon; epsilon subunit of AP-4; epsilon-adaptin (AP4E1)
beta adaptin (adaptor-related protein complex, beta subunit)
beta' adaptin (adaptor-related protein complex 1, beta-1 subunit, clathrin adaptor complex AP1, beta subunit)
clathrin coat assembly protein AP180; clathrin coat-associated protein AP180; 91 kD synaptosomal-associated protein (SNAP91, KIAA0656)
delta adaptin (adaptor-related protein complex, delta subunit)
gamma adaptin (adaptor-related protein complex, gamma subunit)
mu adaptin (adaptor-related protein complex, mu subunit)
sigma adaptin (adaptor-related protein complex sigma subunit, small adaptin)
General
membrane protein
protein subunit
Properties
COMPARTMENT: clathrin coated vesicle
MOTIF: membrane region
References
- Serafini T et al
A coat subunit of Golgi-derived non-clathrin-coated vesicles
with homology to the clathrin-coated vesicle coat protein
beta-adaptin.
Nature. 1991 Jan 17;349(6306):215-20.
PMID: 1898984