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acquired polycystic kidney disease
Etiology:
1) chronic renal insufficiency
2) end-stage renal disease (ESRD)
Epidemiology:
- up to 50% of patients receiving dialysis for more than 5 years
Clinical manifestations:
1) fever
2) pain
3) hematuria
4) infection
5) erythrocytosis
Radiology:
- annual renal ultrasound to screen for renal cell carcinoma in patients who are candidates for renal transplantation
Complications:
1) adenomas in 5-10%
2) adenocarcinomas in 1.5%
- 30-fold increased risk of renal cell carcinoma with acquired form [1]
Management:
- tolvaptan approved for use in autosomal dominant polycystic kidney disease is not useful in acquired form [1]
Interactions
disease interactions
General
polycystic kidney disease
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 17, 19.
American College of Physicians, Philadelphia 1998, 2015, 2021