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acetylcholine (nicotinic) receptor antibody
Etiology:
- occurs in patients with myasthenia gravis (MG).
- occasionally occur in association with:
a) amyotrophic lateral sclerosis (ALS)
b) Lambert-Eaton myasthenic syndrome
c) pernicious anemia
- does NOT occur with congenital myasthenia gravis
- occurs in only 15% of patients with ocular myasthenia gravis
Laboratory:
- nicotinic receptor antibody in serum
Related
cholinergic receptor
General
autoantibody
References
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 651
- Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995