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acetoacetate; beta-ketobutyrate; 3-ketobutyrate
Biochemistry:
- acetoacetate produced in the liver during periods of fasting or exercise
- transfer of CoA from succinyl CoA to form acetoacetyl CoA & subsequently 2 acetyl CoA molecules by thiolase
- acetyl CoA enters the citric acid cycle
Physiology:
- heart muscle & renal cortex prefer acetoacetate as an energy source over glucose
- the brain uses acetoacetate when glucose levels are low due to fasting
Laboratory:
- acetoacetate in blood
- acetoacetate in CSF
- acetoacetate in serum/plasma
- acetoacetate in urine
Interactions
molecular events
Related
acetoacetate in serum/plasma
ketone bodies in body fluid
Specific
acetoacetyl coenzyme A
General
carboxylate
ketone
Database Correlations
PUBCHEM cid=96
References
- Loinc
- Wikipedia: Acetoacetate
https://en.wikipedia.org/wiki/Acetoacetic_acid