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central obesity; abdominal obesity
Pathology:
- central obesity or abdominal obesity is due to excess visceral fat
- central obesity is associated with an increased risk of diabetes mellitus type 2, dysplipidemia, hypertension, & cardiovascular disease & mortality in overweight & obese
- central obesity is associated with cognitive impairment [3]
- central obesity may account for most of the colorectal cancer risk linked to obesity [4]
Clinical manifestations:
- waist circumference & waist/hip ratio identifies central_obesity
- waist/hip >0.9-1.0 in men & >0.85-0.9 in women indicates central obesity
- waist circumference >= 102 cm (40 inches) in men & >= 88 cm (35 inches) in women
General
obesity
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 15, 16,
17, 18, 19. American College of Physicians, Philadelphia 1998, 2009,
2012, 2015, 2018, 2022.
- Medical Knowledge Self Assessment Program (MKSAP) 19
Board Basics. An Enhancement to MKSAP19.
American College of Physicians, Philadelphia 2022
- Emdin CA, Khera AV, Natarajan P et al
Genetic Association of Waist-to-Hip Ratio With Cardiometabolic
Traits, Type 2 Diabetes, and Coronary Heart Disease.
JAMA. 2017;317(6):626-634
PMID: 2819625
http://jamanetwork.com/journals/jama/article-abstract/2601502
- Lin Wy
Associations of five obesity indicators with cognitive performance in 30,697
Taiwan Biobank participants.
BMC Geriatrics. 2022 22:839. Nov 7
PMID: 36344931
https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-022-03457-x
- Safizadeh F, et al.
Colorectal Cancer and Central Obesity.
JAMA Netw Open. 2025.
PMID: 39820694 PMCID: PMC11739990 Free PMC article.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829271
- Safizadeh F, et al.
Central obesity may account for most of the colorectal cancer risk linked to obesity:
evidence from the UK Biobank prospective cohort.
Int J Obes (Lond). 2024.
PMID: 39562688
https://www.nature.com/articles/s41366-024-01680-7