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abacavir/dolutegravir/lamivudine
Indications:
- treatment of HIV1/AIDS
Adverse effects:
- increase in serum creatinine due to inhibition of proximal tubule secretion of creatinine by dolutegravir, not due to decrease in glomerular filtration rate [2]
General
antiretroviral combination
References
- Walmsley SL et al
Dolutegravir plus Abacavir-Lamivudine for the Treatment of
HIV-1 Infection.
N Engl J Med 2013; 369:1807-1818. November 7, 2013
PMID: 24195548
http://www.nejm.org/doi/full/10.1056/NEJMoa1215541
- Medical Knowledge Self Assessment Program (MKSAP) 19.
American College of Physicians, Philadelphia 2021
Components
abacavir (Ziagen, ABC)
dolutegravir (Tivicay, DTG)
dolutegravir/lamivudine (Dovato)
lamivudine (3TC, Epivir)