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B lymphocyte
Function:
- precursor of antibody-producing cell (plasma cell)
- may also function as antibody-presenting cell
Immunophenotype:
- surface immunoglobulin + (usually IgM +/- IgD, IgG, IgA)
- CD19, CD20, CD22, CD79a: + (B-cell surface antigens)
Laboratory:
- B-cell Ag in tissue
- B lymphocytes in blood
- B lymphocytes in bone marrow
Related
B cell markers
Specific
centrocyte
follicular center cell
memory B lymphocyte
General
antibody producing cell
lymphocyte
References
- BioCarta - B cell receptor complex
http://cgap.nci.nih.gov/Pathways/BioCarta/bcrMolecule
- BioCarta - B cell survival pathway
http://cgap.nci.nih.gov/Pathways/BioCarta/bcellsurvivalPathway
- BioCarta - B lymphocyte cell surface molecules
http://cgap.nci.nih.gov/Pathways/BioCarta/blymphocytePathway
- BioCarta - antigen dependent B cell activation
http://cgap.nci.nih.gov/Pathways/BioCarta/asbcellPathway