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6-N-hydroxyaminopurine; N6-hydroxyadenine (6-HAP)

Mechanism of action: - inhibits & interferes with DNA synthesis Comparative biology: - produced by strain of Staphylococcus epidermidis on the skin of mice - protects mice from UV radiation-induced skin cancer [2] - same strain of Staphylococcus epidermidis common on human skin [2]

General

hydroxylamine purine

Database Correlations

PUBCHEM cid=21876

References

  1. PubChem: 21876
  2. Galindo Y Beneficial Skin Bacteria Protect Against Skin Cancer. UC San Diego News Center. Feb 28, 2018 citing study Nakatsuji T, Chen TC, Butcher AM et al published in Science Advances on February 28 https://ucsdnews.ucsd.edu/pressrelease/beneficial_skin_bacteria_protect_against_skin_cancer