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second generation antidepressant

All second generation antidpressants have similar efficacy [1] Also see antidepressant or specific agent Includes: - bupropion - citalopram - duloxetine - escitalopram - fluoxetine - fluvoxamine - mirtazapine - nefazodone - paroxetine - sertraline - trazodone - venlafaxine

Interactions

drug interactions drug adverse effects (more general classes)

Specific

atypical antidepressant selective serotonin reuptake inhibitor (SSRI) trazodone (Desyrel, Pragmazone, Oleptro)

General

antidepressant

References

  1. Gartlehner G et al Comparative Benefits and Harms of Second-Generation Antidepressants for Treating Major Depressive Disorder: An Updated Meta-analysis Annals of Internal Medicine, December 6, 2011, 155(11):772-785 PMID: 22147715 http://www.annals.org/content/155/11/772.abstract
  2. Qaseem A et al. Using second-generation antidepressants to treat depressive disorders: A clinical practice guideline from the American College of Physicians. Ann Intern Med 2008 Nov 18; 149:725. PMID: 19017591 (Corresponding NGC guideline withdrawn Jan 2014) - Gartlehner G et al. Comparative benefits and harms of second-generation antidepressants: Background paper for the American College of Physicians. Ann Intern Med 2008 Nov 18; 149:734. PMID: 19017592