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20S proteasome

Function: - multicatalytic proteinase complex - forms the chamber of the 26S proteasome [3]

Related

19S proteasome (PA700 complex) 20S proteasome inhibitor

General

macromolecular complex

Properties

COMPARTMENT: cell nucleus cytoplasm MISC-INFO: SEDIMENTATION_COEFFICIENT 20 S

Database Correlations

ENZYME 3.4.99.46

References

  1. Tanaka K, Yoshimura T, Tamura T, Fujiwara T, Kumatori A, Ichihara A. Possible mechanism of nuclear translocation of proteasomes. FEBS Lett. 1990 Oct 1;271(1-2):41-6. Review. PMID: 2226812
  2. Allende JE, Allende CC. Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J. 1995 Mar;9(5):313-23. Review. PMID: 7896000
  3. Kosik KS, Shimura H. Phosphorylated tau and the neurodegenerative foldopathies. Biochim Biophys Acta. 2005 Jan 3;1739(2-3):298-310. Epub 2004 Nov 26. Review. PMID: 15615647

Component-of

26S proteasome

Components

LMP-2/ring-12 protein (proteasome subunit beta type-9, proteasome chain 7, macropain chain 7, multicatalytic endopeptidase complex chain 7, RING12 protein, low molecular mass protein 2, PSMB9, LMP2, RING12) LMP-7/ring-10 protein (proteasome subunit beta type-8, macropain-C13 subunit, proteasome component C13, multicatalytic endopeptidase complex subunit C13, PSMB8, LMP7, RING10, Y2) macropain IOTA; proteasome subunit alpha type-6k 27 kD prosomal protein; proteasome IOTA; multicatalytic endopeptidase complex iota chain; 27 kD prosomal protein (IOTA, PROS-27, p27K, PSMA6, PROS27) macropain MECL-1; proteasome subunit beta type-10; proteasome MECL-1; multicatalytic endopeptidase complex subunit MECl-1 (PSMB10, MECL1) macropain-beta 2 subunit; macropain subunit C7-1; proteasome subunit beta type 2; multicatalytic endopeptidase complex subunit C7-1 (PSMB4, PSMB2, HSN3, HsBPROS26) macropain-beta subunit (proteasome beta chain, multicatalytic endopeptidase complex beta chain) macropain-C2 subunit (proteasome subunit alpha type-1, proteasome component C2, proteasome Nu chain, 30 kD prosomal protein, PROS-30, PSMA1, PROS30, PSC2) macropain-C3 subunit (proteasome subunit alpha type-2, proteasome component C3 , multicatalytic endopeptidase complex chain C3, PSMA2, PSC3) macropain-C5 subunit (proteasome subunit beta type-1, proteasome component C5, multicatalytic endopeptidase complex chain C5, proteasome gamma chain, PSMB1, PSC5) macropain-C8 subunit (proteasome subunit alpha type-3, proteasome component C8, multicatalytic endopeptidase complex chain C8, PSMA3, PSC8) macropain-C9 subunit; proteasome subunit alpha type-4; proteasome component C9; multicatalytic endopeptidase complex chain C9 (PSMA4, PSC9) macropain-delta subunit (proteasome delta chain, proteasome subunit beta type-6, PSMB6, LMPY) macropain-epsilon subunit (proteasome subunit beta type-5, macropain beta-5 subunit, proteasome chain 6, proteasome epsilon chain, proteasome subunit X, proteasome subunit MB1, PSMB5, LMPX) macropain-zeta subunit (proteasome subunit alpha type-5, proteasome zeta chain, multicatalytic endopeptidase complex zeta chain, PSMA5) proteasome subunit X or macropain-alpha 3 subunit proteasome subunit Y