Search
1st pass metabolism
Intestinal uptake & degradation within the intestine, liver or portal circulation before a drug or bioagent reaches the systemic circulation. The effect is greater in men than in women [2].References
- Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
- Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004